Astrology continued to be part of mainstream science until the late 1600s, when Isaac Newton demonstrated some of the physical processes by which celestial bodies affect each other. In doing so, he showed that the same laws that make, say, an apple fall from a tree, also apply to the motions of the celestial sphere. Since then, astronomy has evolved into a completely separate field, where predictions about celestial phenomena are made and tested using the scientific method.
In contrast, astrology is now regarded as a pastime and a pseudoscience though thousands of people around the world still invoke advice from astrologers and astrology publications in making important professional, medical, and personal experiences.